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1、PleaseprovideemailaddressandORCIDforallauthors.Pleasevisithttp:/orcid.org/forORCIDregistration.ThemaintextandformaltablesofmanuscriptshouldbepreparedinWordfile,justifiedand1.5spacing.SupplementarytablescanbesubmittedinExcelformat.Standardfiguresizesare85mm(singlecolumn)and175mm(doublecolumn)forwidth
2、verticallyor238mmhorizontally.Pleaseadjustthefontsizeforclarity.Thefigureformatcanbeinppt,ai(illustrator),jpeg.PleaseaddlinenumbersinyourmanuscriptandmakesurethebuiltPDFforsubmissionhasthecorrespondinglinenumberstoo.ThereisnoAbbreviationsection,pleasespellthetermsinfullatfirstmentionandputtheabbrevi
3、ationafterwardsinparenthesis.TitlepageArticleTitleInsertarticletitlehereNote:WecapitalizethefirstletterofeachcontentwordforthearticletitleintheactualarticleandTOC.Forprepositionwords,iftherearemorethan5letters,thefirstlettershouldbeinuppercasetoo.Likebetweenshouldbe“Between”inthetitle.Thetitleshould
4、beinboldandthefontsizeshouldbe15.Aligntotheleft.Sample:TheAssociationBetweenH3K4me3andAntisenseTranscriptionAuthor(s)NamesInsertauthor(s)nameshereFirstNameMiddleNameFamilyNamel,Note:Thereisacommabetweentwonames,no“and”beforethelastauthor,sname.WeprefertousenumbersinsteadOfletterstolabeltheauthors5in
5、stitutionassuperscript.Weprefertouse*topresentthecorrespondingauthor(s),andusetopresenttheequalcontributionauthor(s).Sample:HuanmingYang巴DonaldJ.Zack2*,SongnianHUL,Jun丫/产Author(s)AddressInformationInsertauthor(s)addresshere1 DepartnientZInstitute,University,CityPostalcode,CountrySample:2 BeijingInst
6、ituteofGenotnicsfChineseAcademyofSciences,Beijing101300,China3 DepartmentofMolecularBiologyandGenetics,JohnsHopkinsUniversitySchoolofMedicine,BaltimoreMD2/287,USASymbol#Equalcontribution.+Correspondingauthor(s).E-mail:Correspondingauthor(s)E-mailCorrespondingauthor(s)lastnameandinitialsoffirstandmid
7、dlenames(withacommabetweentwoauthors)SampleforE-mail:E-mail:junyu(YuJ),husn(HuS).Runningtitle:Note:nomorethan50characters,italic;capitalizetheinitialletterofeachcontentwordThefirstauthorname/Runningtitle.Nodotsinbetween.Ifonlytwoauthorscontributedtothework,thenusebothnamesratherthanetal.Sample:Runni
8、ngtitle:YangHetal/CorrelationofH3K4me3andAntisenseTranscriptionRunningtitle:MehrotraSandGoyalV/RepetitiveSatelliteDNAinPlantsPleasealsoindicatethetotalcountsofwords,figures,tables,supplementaryfiguresandsupplementarytables.AbstractpageAbstractInsertabstracthereNote:Thissectionshouldbeinoneparagraph,
9、unstructured,lessthan250words.Sample:AbstractHistoneH3lysine4trimethylation(H3K4me3)iswellknowntooccurinthepromoterregionofgenesfortranscriptionactivation.However,wheninvestigatingtheH3K4me3profilesinthemousecerebrumandtestis,wediscoveredthatH3K4me3alsohasasignificantenrichmentatthe3endofactivelytra
10、nscribed(sense)genes,namedas3H3K4me3.3,-H3K4me3isassociatedwith15%ofprotein-codinggenesinbothtissues.Therefore,wespeculatethatthese3r-H3K4me3-markedregionsmayserveaspotentialpromotersforantisensetranscriptionand3-H3K4me3appeartobeauniversalepigeneticfeatureineukaryotes.Ourresultsprovideanovelinsight
11、intotheepigeneticrolesofH3K4me3andtheregulatorymechanismofantisensetranscription.KEYWORDS:Insertkeywordshere;InsertkeywordshereNote:Thereshouldbe3-5keywords,withasemicolonbetweentwokeywords,andcapitalizethefirstletterofeachkeyword.Keywordusedtoextendthesearchablepossibilitiesforyoumanuscript,thusiti
12、srecommendedtousewordsthatdidnotappearinthearticletitle.Sample:KEYWORDS:Calciumtransporter;Sorghum;Rice;GenomicannotationTextbodypageThroughoutthepaper,pleasechecktheusageofproteinandgenesymbols,abbreviations,andnames.Proteinabbreviations/symbolsarenormallyinRomanfont(uprighttype),whilethegenesymbol
13、s/namesshouldbeinitalics,normallyinuppercaseforhumangenes(e.g.,CMHlandHPR)andinlowercasewithaninitialcapitalforanimalgenes(viz.mouse;e.g.,HraslandTcra).IntroductionInsertintroductionhereNote:Noindentbeforethe1stparagraphofaseparatesectionisnecessary.Usesquarebrackettoshowthereferencenumberinthetext1
14、.Andnumberthereferencesaccordingtotheorderoffirstappearanceinthetext.The1stparagraphshouldaligntotheleft,withnoindent.However,formthe2ndparagraph,thereshouldbea3-letterindent.1.5spacesarerecommendedthroughoutthewholemanuscript.Sample:IntroductionThemembrane-associatedcalciumtransporterproteinsareess
15、entialtomaintaincalciumhomeostasisundernormalphysiologicalconditionsandprovidetoleranceagainstvariousstresses.Therearethreemajorclassesofcalciumtransporterproteins:channels,ATPases(pumps)andexchangers16.Membersofthesetransporterproteinsmaydifferintheircellularandtissuedistributionandregulationbyothe
16、rsignalingpathways7,8.ThespatialandtemporalregulationOfcalciumconcentrationinplantcellsdependsonthecoordinatedactivitiesofchannelsandactivetransporterslocatedondifferentorganellesandmembranes9.ResultsInsertresultshereNote:TheIst-Ieveltitleshouldbeinthefontsizeof14andinbold.The2nd-leveltitleshouldbeinbol
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